Chronic intestinal pseudo-obstruction (CIP) is a rare, potentially disabling gastrointestinal disorder characterized by abnormalities affecting the involuntary, coordinated muscular contractions (a process called peristalsis) of the gastrointestinal (GI) tract. Intestinal pseudo-obstruction may be acute, occurring suddenly and lasting a short time, or it may be chronic, or long lasting. Acute colonic pseudo-obstruction, also called Ogilvie syndrome or acute colonic ileus, mostly affects older adults.
May 21, 2008 · INTRODUCTION. Chronic intestinal pseudo-obstruction (CIPO) is a rare, severe disease characterized by the failure of the intestinal tract to propel its contents which results in a clinical picture mimicking mechanical obstruction in the absence of any lesion occluding the gut. CIPO is one of the most important causes of chronic intestinal failure Cited by: 160. Although pediatric and adult chronic intestinal pseudo-obstruction share many clinical aspects distinctive features can be identified. There is no single diagnostic test or pathognomonic finding of CIPO, thus a stepwise approach including radiology, endoscopy, laboratory, manometry and histopathology should be considered in the diagnostic work-up.
Natural History of Chronic Idiopathic Intestinal Pseudo-Obstruction in Adults: A Single Center Study VINCENZO STANGHELLINI, ROSANNA F. COGLIANDRO, ROBERTO DE GIORGIO, GIOVANNI BARBARA, ANTONIO M. MORSELLI–LABATE, LAURA COGLIANDRO, and ROBERTO CORINALDESI Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy. Intestinal Pseudo-Obstruction. Intestinal pseudo-obstruction can occur in people of any age, but it occurs more often in children and older adults. Children can have a long-lasting form of the condition called chronic intestinal pseudo-obstruction (CIP). CIP in children is usually present at birth.
Background—Chronic idiopathic intestinal pseudo-obstruction, a syndrome of ineffectual motility due to a primary disorder of enteric nerve or muscle, is rare. Aims —To determine the clinical spectrum, underlying pathologies, response to treatments, and prognosis in Cited by: 221. Pseudo-obstruction may be acute or chronic and is characterized by the presence of dilation of the bowel on imaging. When there is evidence of chronic small intestinal motility disorder in the absence of bowel dilatation, the preferred term is chronic intestinal dysmotility.
In primary chronic intestinal pseudo-obstruction (the majority of chronic cases), the condition may be caused by an injury to the smooth muscle (myopathic) or the nervous system (neuropathic) of the gastrointestinal tract. In some cases there appears to be a genetic association. One form has been associated with DXYS154.Specialty: Gastroenterology.